mBio
(Apr 2021)
An Alternative and Conserved Cell Wall Enzyme That Can Substitute for the Lipid II Synthase MurG
L. Zhang,
K. Ramijan,
V. J. Carrión,
L. T. van der Aart,
J. Willemse,
G. P. van Wezel,
D. Claessen
Affiliations
L. Zhang
Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
K. Ramijan
Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
V. J. Carrión
Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
L. T. van der Aart
ORCiD Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
J. Willemse
Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
G. P. van Wezel
ORCiD Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
D. Claessen
ORCiD Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands
DOI
https://doi.org/10.1128/mBio.03381-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
Almost all bacteria are surrounded by a cell wall, which protects cells from environmental harm. Formation of the cell wall requires the precursor molecule lipid II, which in bacteria is universally synthesized by the conserved and essential lipid II synthase MurG.
WeChat QR code
Close
