Southern African Journal of Infectious Diseases (Mar 2024)

SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV

  • Lisa Frigati,
  • Leonore Greybe,
  • Shaun Barnabas,
  • Mark Cotton,
  • Helena Rabie

DOI
https://doi.org/10.4102/sajid.v39i1.579
Journal volume & issue
Vol. 39, no. 1
pp. e1 – e3

Abstract

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Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Therapy (CHER) study were collected. We present a descriptive analysis of 53 ALPHIV who were tested for anti-SARS-CoV-2 antibodies. Just over half (53%) of the adolescents tested had positive anti-SARS-CoV-2 antibodies with only one participant describing a prior history of possible symptomatic infection. Contribution: The study contributes to the understanding of SARS-CoV-2 infection and vaccination practices in HIV-positive adolescents.

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