Highly Sensitive and Selective Dopamine Determination in Real Samples Using Au Nanoparticles Decorated Marimo-like Graphene Microbead-Based Electrochemical Sensors
Qichen Tian,
Yuanbin She,
Yangguang Zhu,
Dan Dai,
Mingjiao Shi,
Wubo Chu,
Tao Cai,
Hsu-Sheng Tsai,
He Li,
Nan Jiang,
Li Fu,
Hongyan Xia,
Cheng-Te Lin,
Chen Ye
Affiliations
Qichen Tian
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Yuanbin She
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Yangguang Zhu
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Dan Dai
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Mingjiao Shi
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Wubo Chu
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Tao Cai
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Hsu-Sheng Tsai
Laboratory for Space Environment and Physical Sciences, Harbin Institute of Technology, Harbin 150001, China
He Li
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Nan Jiang
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Li Fu
College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China
Hongyan Xia
State Key Laboratory for Mechanical Behavior of Materials, Xi’an Jiaotong University, Xi’an 710049, China
Cheng-Te Lin
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
Chen Ye
Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China
A sensitive and selective electrochemical dopamine (DA) sensor has been developed using gold nanoparticles decorated marimo-like graphene (Au NP/MG) as a modifier of the glassy carbon electrode (GCE). Marimo-like graphene (MG) was prepared by partial exfoliation on the mesocarbon microbeads (MCMB) through molten KOH intercalation. Characterization via transmission electron microscopy confirmed that the surface of MG is composed of multi-layer graphene nanowalls. The graphene nanowalls structure of MG provided abundant surface area and electroactive sites. Electrochemical properties of Au NP/MG/GCE electrode were investigated by cyclic voltammetry and differential pulse voltammetry techniques. The electrode exhibited high electrochemical activity towards DA oxidation. The oxidation peak current increased linearly in proportion to the DA concentration in a range from 0.02 to 10 μM with a detection limit of 0.016 μM. The detection selectivity was carried out with the presence of 20 μM uric acid in goat serum real samples. This study demonstrated a promising method to fabricate DA sensor-based on MCMB derivatives as electrochemical modifiers.
