Nature Communications (May 2020)

Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring

  • Verginia C. Cuzon Carlson,
  • Christina M. Gremel,
  • David M. Lovinger

DOI
https://doi.org/10.1038/s41467-020-16385-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

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Alcohol is the leading cause of preventable birth defects in the US, collectively referred to as Fetal Alcohol Spectrum Disorder. Here, the authors show that fetal alcohol exposure induces lasting neurophysiological changes in dorsal striatum that contribute to less efficient decision making.