The Effect of Far-Infrared Therapy on the Peritoneal Membrane Transport Characteristics of Uremic Patients Undergoing Peritoneal Dialysis: An Open-Prospective Proof-of-Concept Study
Ching-Po Li,
Chyong-Mei Chen,
Chia-Hao Chan,
Szu-Yuan Li,
Ming-Tsun Tsai,
Chun-Fan Chen,
Yung-Tai Chen,
Tz-Heng Chen,
Fan-Yu Chen,
Ching-Han Yang,
Yi-Hsin Chou,
Tsung-Yueh Wang,
Ann Charis Tan,
Chih-Ching Lin
Affiliations
Ching-Po Li
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Chyong-Mei Chen
Institute of Public Health, School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Chia-Hao Chan
Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan
Szu-Yuan Li
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Ming-Tsun Tsai
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Chun-Fan Chen
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Yung-Tai Chen
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Tz-Heng Chen
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Fan-Yu Chen
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Ching-Han Yang
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Yi-Hsin Chou
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Tsung-Yueh Wang
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Ann Charis Tan
Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan
Chih-Ching Lin
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan
Long-term peritoneal dialysis (PD) can lead to detrimental changes in peritoneal membrane function, which may be related to the accumulation of glucose degradation products. A previous study demonstrated that 6 months of far-infrared (FIR) therapy may decrease glucose degradation products in PD dialysate. Due to limited literature on this matter, this study aims to investigate the effect of FIR therapy on the peritoneal membrane transport characteristics of PD patients. Patients were grouped according to baseline peritoneal transport status: lower transporters (low and low-average) and higher transporters (high-average and high). Both groups underwent 40 min of FIR therapy twice daily for 1 year. In lower transporters, FIR therapy increased weekly dialysate creatinine clearance (6.91 L/wk/1.73 m2; p = 0.04) and D/P creatinine (0.05; p = 0.01). In higher transporters, FIR therapy decreased D/P creatinine (−0.05; p = 0.01) and increased D/D0 glucose (0.05; p = 0.006). Fifty percent of high transporter patients shifted to high-average status after FIR therapy. FIR therapy may decrease D/P creatinine for patients in the higher transporter group and cause high transporters to shift to high-average status, which suggests the potential of FIR therapy in improving peritoneal membrane function in PD patients.
