Controlled packing and single-droplet resolution of 3D-printed functional synthetic tissues

Alessandro Alcinesio; Oliver J. Meacock; Rebecca G. Allan; Carina Monico; Vanessa Restrepo Schild; Idil Cazimoglu; Matthew T. Cornall; Ravinash Krishna Kumar; Hagan Bayley

doi:10.1038/s41467-020-15953-y

Nature Communications (Apr 2020)

Controlled packing and single-droplet resolution of 3D-printed functional synthetic tissues

Alessandro Alcinesio,
Oliver J. Meacock,
Rebecca G. Allan,
Carina Monico,
Vanessa Restrepo Schild,
Idil Cazimoglu,
Matthew T. Cornall,
Ravinash Krishna Kumar,
Hagan Bayley

Affiliations

Alessandro Alcinesio: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Oliver J. Meacock: Department of Zoology, University of Oxford, Zoology Research & Administration Building
Rebecca G. Allan: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Carina Monico: Micron Advanced Bioimaging Unit, Department of Biochemistry, University of Oxford
Vanessa Restrepo Schild: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Idil Cazimoglu: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Matthew T. Cornall: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Ravinash Krishna Kumar: Department of Chemistry, University of Oxford, Chemistry Research Laboratory
Hagan Bayley: Department of Chemistry, University of Oxford, Chemistry Research Laboratory

DOI: https://doi.org/10.1038/s41467-020-15953-y
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Precise patterning of lipid-stabilised aqueous droplets is a key challenge in building synthetic tissue designs. Here, the authors show how the interactions between pairs of droplets direct the packing of droplets within 3D-printed networks, enabling the formation of synthetic tissues with high-resolution features.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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