Nature Communications (Mar 2017)

Synthesizing topological structures containing RNA

  • Di Liu,
  • Yaming Shao,
  • Gang Chen,
  • Yuk-Ching Tse-Dinh,
  • Joseph A. Piccirilli,
  • Yossi Weizmann

DOI
https://doi.org/10.1038/ncomms14936
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 10

Abstract

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In vivo, complex topologies have been identified in proteins and DNA, while their existence in RNA is still unclear. Here, the authors design synthetic topological structures containing single stranded RNA, offering tools for investigating biologically relevant questions about RNA topology.