Cancers (Sep 2023)

Minimally-Invasive Secondary Cytoreduction in Recurrent Ovarian Cancer

  • Camilla Certelli,
  • Silvio Andrea Russo,
  • Luca Palmieri,
  • Aniello Foresta,
  • Luigi Pedone Anchora,
  • Virginia Vargiu,
  • Francesco Santullo,
  • Anna Fagotti,
  • Giovanni Scambia,
  • Valerio Gallotta

DOI
https://doi.org/10.3390/cancers15194769
Journal volume & issue
Vol. 15, no. 19
p. 4769

Abstract

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The role of secondary cytoreductive surgery (SCS) in the treatment of recurrent ovarian cancer (ROC) has been widely increased in recent years, especially in trying to improve the quality of life of these patients by utilising a minimally-invasive (MI) approach. However, surgery in previously-treated patients may be challenging, and patient selection and surgical planning are crucial. Unfortunately, at the moment, validated criteria to select patients for MI-SCS are not reported, and no predictors of its feasibility are currently available, probably due to the vast heterogeneity of recurrence patterns. The aim of this narrative review is to describe the role of secondary cytoreductive surgery and, in particular, minimally-invasive procedures, in ROC, analyzing patient selection, outcomes, criticisms, and future perspectives.

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