Nature Communications (Apr 2019)

Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcome

  • Supriya Ravichandran,
  • Megan Hahn,
  • Pablo F. Belaunzarán-Zamudio,
  • José Ramos-Castañeda,
  • Gabriel Nájera-Cancino,
  • Sandra Caballero-Sosa,
  • Karla R. Navarro-Fuentes,
  • Guillermo Ruiz-Palacios,
  • Hana Golding,
  • John H. Beigel,
  • Surender Khurana

DOI
https://doi.org/10.1038/s41467-019-09914-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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In the current study, the authors profile the IgG and IgM antibody repertoires that develop over 7 days following acute Zika virus infection. Using urine and serum samples from infected human patients the authors identify new biomarkers for serodiagnosis of Zika virus.