Microalbuminuria in Patients with Acute Ischemic Stroke

Abstract

INTRODUCTION[|]This study aims to investigate the presence of microalbuminuria (MAU) as a risk factor in patients with acute ischemic stroke (AIS).[¤]METHODS[|]Thirty patients (19 female and 11 male; mean age 69.4+-11.9 years) hospitalized with the diagnosis of acute ischemic stroke were enrolled in this study. Microalbuminuria was assessed from the urine samples of patients obtained within 24 hours after the onset of ischemic stroke. Microalbuminuria was accepted as normal if the level was less than 30 mg/day and as high if the level was between 30-300 mg/day. Data obtained were compared with the data of the controls (16 female, 14 male; meanage 64.9+-14.2).[¤]RESULTS[|]A significant difference was not detected between the patients and the control groups for gender and mean ages. When data of the cases with AIS and data of the control group were compared, the mean microalbuminuria level of the AIS group was significantly higher than the control group. Microalbuminuria was present in 23 (76.6%) cases with AIS. Hypertension, diabetes mellitus, recent ischemic stroke, hypercholesterolemia, alcohol and smoking were found in 16 (53.3%), 9 (30.1%), 5 (16.6%), 18 (60.2%), 10 (33.3%), 12 (40.7%) cases with AIS, respectively. The incidence of microalbuminuria in cases with hypertension, diabetes, recent ischemic stroke, and cigarette smoking was significantly higher. Microalbuminuria was found in two (6.3%) cases of the control group.[¤]DISCUSSION AND CONCLUSION[|]Our findings support the hypothesis that microalbuminuria may be a risk factor of ischemic stroke.[¤]

Keywords

• acute ischemic stroke
• cerebrovascular disease; microalbuminuria.