Data highlighting the effects of spinal segmental stimulation of preganglionic sympathetic neurons on the electrophysiology of the rabbit heart
Reshma A. Chauhan,
John Coote,
Emily Allen,
Pott Pongpaopattanakul,
Kieran E. Brack,
G. Andre Ng
Affiliations
Reshma A. Chauhan
Department of Cardiovascular Sciences, University of Leicester, UK
John Coote
Department of Cardiovascular Sciences, University of Leicester, UK; University of Birmingham, UK
Emily Allen
Department of Cardiovascular Sciences, University of Leicester, UK
Pott Pongpaopattanakul
Department of Cardiovascular Sciences, University of Leicester, UK
Kieran E. Brack
Department of Cardiovascular Sciences, University of Leicester, UK
G. Andre Ng
Department of Cardiovascular Sciences, University of Leicester, UK; NIHR Leicester Cardiovascular Biomedical Research Centre, Leicester, UK; University Hospitals of Leicester NHS Trust, Leicester, UK; Corresponding author at: Department of Cardiovascular Sciences, University of Leicester, UK.
This article presents data highlighting the functional selectivity of cardiac preganglionic sympathetic neurons in the rabbit heart. Specifically, the data draw attention to the role of each spinal segmental outflow on cardiac electrophysiology and the influence of each segment on cardiac excitability through investigating markers of arrhythmia such as electrical restitution. This data holds importance for exploring whether the preganglionic sympathetic neurons have functionally distinct pathways to the heart and whether some spinal segmental outflows have a greater potential for arrhythmia generation than others. Discussion of the data can be found in Chauhan et al. (2018) [1].
