Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone

• Maria Rosa Lidonnici,
• Annamaria Aprile,
• Marta Claudia Frittoli,
• Giacomo Mandelli,
• Ylenia Paleari,
• Antonello Spinelli,
• Bernhard Gentner,
• Matilde Zambelli,
• Cristina Parisi,
• Laura Bellio,
• Elena Cassinerio,
• Laura Zanaboni,
• Maria Domenica Cappellini,
• Fabio Ciceri,
• Sarah Marktel,
• Giuliana Ferrari

Affiliations

Maria Rosa Lidonnici

San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy;Vita-Salute San Raffaele University, Milan, Italy

Annamaria Aprile

San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy;Università degli Studi di Roma “Tor Vergata”, Italy

Marta Claudia Frittoli

Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Giacomo Mandelli

San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy

Ylenia Paleari

San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy;Vita-Salute San Raffaele University, Milan, Italy

Antonello Spinelli

Experimental Imaging Centre, San Raffaele Scientific Institute, Milan, Italy

Bernhard Gentner

Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Matilde Zambelli

Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Cristina Parisi

Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Laura Bellio

Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Elena Cassinerio

Università di Milano, Ca Granda Foundation IRCCS, Italy

Laura Zanaboni

Università di Milano, Ca Granda Foundation IRCCS, Italy

Maria Domenica Cappellini

Università di Milano, Ca Granda Foundation IRCCS, Italy

Fabio Ciceri

Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Sarah Marktel

Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Giuliana Ferrari

San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy;Vita-Salute San Raffaele University, Milan, Italy