Nature Communications (Jul 2019)

Structural basis for transcription antitermination at bacterial intrinsic terminator

  • Linlin You,
  • Jing Shi,
  • Liqiang Shen,
  • Lingting Li,
  • Chengli Fang,
  • Chengzhi Yu,
  • Wenbo Cheng,
  • Yu Feng,
  • Yu Zhang

DOI
https://doi.org/10.1038/s41467-019-10955-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Bacteriophages reprogram the host transcriptional machinery. Here the authors provide insights into the mechanism of how bacteriophages regulate host transcription by determining the cryo-EM structures of two bacterial transcription elongation complexes bound with the bacteriophage master host-transcription regulator protein P7.