Investigation the Effect of High-Frequency Noise Exposure on Obesity, Food Intake, and Abdominal Visceral Fat in Adult Male Guinea Pigs

Abstract

Introduction: Obesity and overweight are major global health challenges. One of the bad effects of noise that has been recently expressed is the effect of noise on obesity. This study aimed to investigate the effect of high-frequency noise exposure on obesity, food intake, and abdominal visceral fat in adult male guinea pigs. Material and Methods: The animals in this study were 24 adult male guinea pigs randomly divided into 3 groups (control and two case groups). Each case group was separately exposed to high- frequency white noise with sound pressure levels in 65 dB and 85 dB for 5 days per week in 30 days. The food intake was measured daily. The weight of animals was measured at the start and on days 6, 12, 18, 24, and at the end of exposure period. The abdominal visceral fat was extracted and weighted at the end of the study period. The data were assessed using SPSS V.22 software. Results: ANOVA analysis showed that exposure to high-frequency noise at 65dB and 85dB had a significant effect on weight gain, food intake, and abdominal visceral fat weight (P-value< 0.05) which in the group exposed to the noise with 65 dB was more than other groups. Conclusion: Based on this study, exposure to high-frequency noise may be an effective factor in obesity and increasing abdominal visceral fat. Further studies are needed to investigate the mechanism affecting weight status following noise exposure.

Keywords

• high frequency noise
• obesity
• abdominal visceral fat
• guinea pigs