Gene expression drives the evolution of dominance

Christian D. Huber; Arun Durvasula; Angela M. Hancock; Kirk E. Lohmueller

doi:10.1038/s41467-018-05281-7

Nature Communications (Jul 2018)

Gene expression drives the evolution of dominance

Christian D. Huber,
Arun Durvasula,
Angela M. Hancock,
Kirk E. Lohmueller

Affiliations

Christian D. Huber: Department of Ecology and Evolutionary Biology, University of California
Arun Durvasula: Department of Human Genetics, David Geffen School of Medicine, University of California
Angela M. Hancock: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research
Kirk E. Lohmueller: Department of Ecology and Evolutionary Biology, University of California

DOI: https://doi.org/10.1038/s41467-018-05281-7
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 11

Abstract

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Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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