317 B7-H3-targeted CAR T cell with an inducible caspase 9 suicide gene effectively eradicates uveal melanoma liver metastases

• Yi Sun,
• Cristina R Ferrone,
• Rizwan Haq,
• Soldano Ferrone,
• Genevieve M Boland,
• Sandra Ryeom,
• Russell W Jenkins,
• Giulia Cattaneo,
• Marco Ventin,
• Shahrzad Arya,
• Jingyu Jia,
• Luke Maggs,
• Xinhui Wang,
• Bruce R Ksander

Affiliations

Yi Sun

1 Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, China

Cristina R Ferrone

3 Depatment of General and Gastrointestinal Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA

Rizwan Haq

6Broad Institute of MIT and Harvard, Cambridge, MA, USA

Soldano Ferrone

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Genevieve M Boland

1Massachusetts General Hospital, Boston, MA, USA

Sandra Ryeom

1Columbia University Medical Center, New York, NY, USA

Russell W Jenkins

2Massachusetts General Hospital, Boston, MA, USA

Giulia Cattaneo

1Massachusetts General Hospital, Boston, MA, USA

Marco Ventin

1Massachusetts General Hospital, Boston, MA, USA

Shahrzad Arya

1Massachusetts General Hospital, Boston, MA, USA

Jingyu Jia

1Massachusetts General Hospital, Boston, MA, USA

Luke Maggs

1Massachusetts General Hospital, Boston, MA, USA

Xinhui Wang

1Massachusetts General Hospital, Boston, MA, USA

Bruce R Ksander

7Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA