Nature Communications (Aug 2018)

The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia

  • Nils Otto,
  • Zvonimir Marelja,
  • Andreas Schoofs,
  • Holger Kranenburg,
  • Jonas Bittern,
  • Kerem Yildirim,
  • Dimitri Berh,
  • Maria Bethke,
  • Silke Thomas,
  • Sandra Rode,
  • Benjamin Risse,
  • Xiaoyi Jiang,
  • Michael Pankratz,
  • Silke Leimkühler,
  • Christian Klämbt

DOI
https://doi.org/10.1038/s41467-018-05645-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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In Drosophila, ensheathing glia encase the neuropil but their function is not well understood. Here the authors show a surprising role of ensheathing glia in regulating glutamate homeostasis and locomotion which is controlled by the sulfite oxidase Shopper.