Diagnosis and management of hemolytic uremic syndrome in children: A transfusionist's perspective

Abstract

Hemolytic uremic syndrome (HUS) is one of the important causes of severe acute kidney injury in children. Among many etiologies which are responsible for this syndrome, herein we are reporting two interesting cases of HUS caused by anticomplement factor H autoantibodies and Streptococcus pneumoniae infection where the transfusion medicine department played a crucial role in early diagnosis and prompt management.

Keywords

• atypical hemolytic uremic syndrome
• pneumococcal hemolytic uremic syndrome
• therapeutic plasma exchange
• thomsen-friedenreich antigen