Nature Communications (Apr 2022)

Vasa nucleates asymmetric translation along the mitotic spindle during unequal cell divisions

  • Ana Fernandez-Nicolas,
  • Alicia Uchida,
  • Jessica Poon,
  • Mamiko Yajima

DOI
https://doi.org/10.1038/s41467-022-29855-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Association of mRNA translation with the mitotic spindle is thought to be involved in localized production of cell fate determinants. Here, the authors show Vasa facilitates asymmetric translation, which contributes to differential regulation during sea urchin embryogenesis.