Quantitative evaluation of an optimized Time of Flight Magnetic Resonance Imaging procedure using a phantom setup to simulate aqueous humor flow
Thomas Wecker,
Christian van Oterendorp,
Wilfried Reichardt
Affiliations
Thomas Wecker
Eye Center, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; Wecker Eye Center, Heilbronn, Germany
Christian van Oterendorp
Department of Ophthalmology, Georg-August University Hospital, Göttingen, Germany
Wilfried Reichardt
Medical Physics, Department of Radiology, Faculty of Medicine, University of Freiburg, Germany; German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Correspondence to: UNIVERSITÄTSKLINIKUM FREIBURG, Medical Physics, Department of Radiology, Breisacherstr. 60a, 79106 Freiburg, Germany.
Preclinical Magnetic Resonance Imaging at high field strength offers the great advantage of combining anatomical information and very high resolution of down to 25 µm in mice and even higher resolutions in ex vivo settings. The presented data is Time of Flight MR imaging data using a tube phantom and a given flow-rate to determine the lower limit of the flow rate that is detectable with an experimental set-up and a specifically optimized 2D TOF sequence.In this work we present data on a phantom study which shows the ability of Time of Flight MR Imaging to detect very low flow rates down to 25 µl/h at a velocity of 0.1 mm/s non-invasively in a phantom study.
