A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi

Abstract

A new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The absolute configuration of the secondary alcohol in 1 was confirmed by Mosher's method. Compound 2 exhibited significant anti-inflammatory activity with IC50 value of 6.72 μmol/L.

Keywords

• Illicium difengpi
• Sesquiterpene lactone
• Aromatic glycoside
• Mosher's method
• Anti-inflammatory activities