Relationship between severity of mitral regurgitation and renal function in patients with ischemic chronic heart failure

Abstract

Mitral regurgitation (MR) - frequent complication of prolonged and severe coronary artery disease, left ventricular systolic dysfunction (LV) of different genesis and plays an important role in the onset and progression of chronic heart failure (CHF). Aim. In order to identify relationships between severity of mitral regurgitation and renal function 318 patients with ischemic chronic heart failure were included. Methods and results. Biochemical analysis was used for study of the filtration capacity of the kidneys, echocardiography – the structural and functional parameters of the heart. It was established that the increase in severity of mitral regurgitation sweeping in chronic heart failure accompanied by a decline of kidney function, left ventricular ejection fraction, increase in left atrial volume index, increased systolic pulmonary artery pressure and E/Eann ratio increase. Conclusions. This indicates that mitral regurgitation formation of on the background of abnormal left ventricular remodeling in patients with ischemic chronic heart failure is associated with a reduction of kidney function and needs more attention in order to be detected at an earlier stage.

Keywords

• Heart Failure;
• Mitral Regurgitation
• Kidney