Children (Aug 2017)

Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients

  • Hillary Orr,
  • Deni Trone,
  • Joshua Elder,
  • Ashok Raj

DOI
https://doi.org/10.3390/children4090079
Journal volume & issue
Vol. 4, no. 9
p. 79

Abstract

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This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10–20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10–20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents.

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