Bladder and bowel: friends or enemies?

Abstract

Overactive bladder (OAB) is a very common condition. OAB undoubtedly requires correction since it significantly affects the patient’s quality of life. Literature review showed that pharmacokinetic and metabolic characteristics of trospium chloride make it a drug of choice in elderly and comorbid patients. There is a clear correlation between intestine and bladder dysfunction. The effects of rebamipide discovered by experiments, such as restoration of the damaged urothelium structure and function, as well as suppression of the overactive bladder, require further in-depth study and introduction of the drug to clinical practice for treatment of patients with chronic cystitis and OAB.

Keywords

• bladder
• intestines
• overactive bladder
• capillary leak syndrome
• trospium chloride
• rebamipide