Nature Communications (Aug 2018)

Architecture of the native major royal jelly protein 1 oligomer

  • Wenli Tian,
  • Min Li,
  • Huiyuan Guo,
  • Wenjun Peng,
  • Xiaofeng Xue,
  • Yifan Hu,
  • Yang Liu,
  • Yazhou Zhao,
  • Xiaoming Fang,
  • Kai Wang,
  • Xiuting Li,
  • Yufeng Tong,
  • Michael A. Conlon,
  • Wei Wu,
  • Fazheng Ren,
  • Zhongzhou Chen

DOI
https://doi.org/10.1038/s41467-018-05619-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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Major royal jelly protein 1 (MRJP1) is the most abundant glycoprotein in royal jelly (RJ). Here the authors isolated MRJP1 from RJ and determined the 2.65 Å resolution crystal structure of the 16-molecule oligomer, which also contained 24-methylenecholesterol and apisimin bound to MRJP1.