Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy

• Andreas Greinacher,
• Florian Langer,
• Linda Schonborn,
• Thomas Thiele,
• Munif Haddad,
• Thomas Renne,
• Jerome Rollin,
• Yves Gruel,
• Theodore E. Warkentin

Affiliations

Andreas Greinacher

Institut fur Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitatsmedizin Greifswald

Florian Langer

Zentrum fur Onkologie, II. Medizinische Klinik und Poliklinik, Universitatsklinikum Eppendorf, Hamburg

Linda Schonborn

Institut fur Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitatsmedizin Greifswald

Thomas Thiele

Institut fur Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitatsmedizin Greifswald

Munif Haddad

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg

Thomas Renne

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Center for Thrombosis and Hemostasis (CTH), Johannes Gutenberg University Medical Center, Mainz, Germany; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin

Jerome Rollin

Regional University Hospital Centre Tours, Department of Haemostasis, Tours, France; University of Tours, EA7501 GICC, Tours

Yves Gruel

Regional University Hospital Centre Tours, Department of Haemostasis, Tours, France; University of Tours, EA7501 GICC, Tours

Theodore E. Warkentin

Dept. of Pathology and Molecular Medicine, and Dept. of Medicine, McMaster University, Hamilton, Ontario