Antiaging and Skin Irritation Potential of Four Main Indonesian Essential Oils
Dwinna Rahmi,
Retno Yunilawati,
Bumiarto Nugroho Jati,
Ira Setiawati,
Arief Riyanto,
Irmanida Batubara,
Rika Indri Astuti
Affiliations
Dwinna Rahmi
Balai Besar Kimia dan Kemasan, Kementerian Perindustrian Republic of Indonesia, Jl. Balai Kimia I Pekayon, Pasar Rebo, Jakarta Timur 13710, Indonesia
Retno Yunilawati
Balai Besar Kimia dan Kemasan, Kementerian Perindustrian Republic of Indonesia, Jl. Balai Kimia I Pekayon, Pasar Rebo, Jakarta Timur 13710, Indonesia
Bumiarto Nugroho Jati
Balai Besar Kimia dan Kemasan, Kementerian Perindustrian Republic of Indonesia, Jl. Balai Kimia I Pekayon, Pasar Rebo, Jakarta Timur 13710, Indonesia
Ira Setiawati
Balai Besar Kimia dan Kemasan, Kementerian Perindustrian Republic of Indonesia, Jl. Balai Kimia I Pekayon, Pasar Rebo, Jakarta Timur 13710, Indonesia
Arief Riyanto
Balai Besar Kimia dan Kemasan, Kementerian Perindustrian Republic of Indonesia, Jl. Balai Kimia I Pekayon, Pasar Rebo, Jakarta Timur 13710, Indonesia
Irmanida Batubara
Pusat Studi Biofarmaka Tropika Institut Pertanian Bogor, Kampus IPB Taman Kencana, Jl. Taman Kencana No. 3, Bogor, RT.03/RW.03, Babakan, Kecamatan Bogor Tengah, Kota Bogor 16128, Indonesia
Rika Indri Astuti
Pusat Studi Biofarmaka Tropika Institut Pertanian Bogor, Kampus IPB Taman Kencana, Jl. Taman Kencana No. 3, Bogor, RT.03/RW.03, Babakan, Kecamatan Bogor Tengah, Kota Bogor 16128, Indonesia
Essential oils possess antiaging properties due to their antioxidant activity. This study aims to determine the antiaging activities of four main Indonesian essential oils and their irritation potential on the skin. The spot yeast and in vivo rat skin with UVB exposure methods were used to analyze the antiaging activity of essential oils on aging triggered by endogenous and exogenous factors, respectively. Meanwhile, patch tests and clinical evaluations were used for the skin irritation potential analysis. The antiaging activity results from the endogenous factor showed that the use of clove, patchouli, nutmeg, and citronella oils increased yeast viability at concentrations of 20, 40, 60, and 100 µg/mL, respectively. Furthermore, nutmeg, cloves, citronella, and patchouli oils decreased the wrinkle score on rat skin after UVB exposure (exogenous factor). The skin irritation potential results of patchouli, nutmeg, citronella, and clove oils were none (0), slightly (0.02), moderately (0.09), and very irritating (0.39), respectively.
