Predictors of No-reflow Phenomenon Development in Patients Presenting with ST Segment Elevated Myocardial Infarction and Treated with Primary Percutaneous Coronary Intervention

Abstract

Objective: No-reflow phenomenon is one of well-known complications of percutaneous coronary intervention (PCI). The rate of no-reflow phenomenon was reported between 2-44% differing on the accompanying situations and more frequent in acute myocardial infarction. Predictive factors for no-reflow phenomenon have not been clearly defined. We aimed to define predictive factors for no-reflow development in patients who presented with ST-segment elevation MI (STEMI) and treated with primary (PPCI). Method: Patients who underwent PPCI between 2017 and 2021 in our clinic were included retrospectively. Demographic, clinical and laboratory findings were recorded. Two groups generated according to no-reflow development: no-reflow (+) and (-). Results: Six hundred eighty-nine patients were included. Mean age was 55.9±8.7 years and 71.8% were male. 107 patients (15.5%) were formed no-reflow (+) group and 582 patients were formed no-reflow (-) group. Left ventricular ejection fraction, troponin, fasting blood glucose, TIMI thrombus grade and TIMI thrombus category were determined as independent predictors of no-reflow development. Conclusion: Considering the relationship between no-reflow development and adverse outcomes such as in-hospital adverse cardiac events, left ventricular remodeling, malignant ventricular arrhythmia, or heart failure, it may help to identify the factors that predict the risk of no-reflow and take preventive measures to improve the long-term outcome.

Keywords

• no-reflow
• st elevation myocardial infarction
• timi thrombus grade