Fatal fulminant cryptococcemia complicating sarcoidosis: Is it to be expected?

Abstract

Cryptococcosis may be a life-threatening complication of sarcoidosis. We describe a case of cryptococcemia that rapidly progressed toward fatality without apparent other sites of infection. We discuss on the importance of serum cryptococcal polysaccharide antigen testing for identifying at-risk patients who might benefit from timely diagnosis and treatment of cryptococcosis. Keywords: Cryptococcus neoformans, Cryptococcemia, Sarcoidosis, Capsular antigen, Diagnostic biomarkers