Indole-Containing Metal Complexes and Their Medicinal Applications
Zahra Kazemi,
Hadi Amiri Rudbari,
Nakisa Moini,
Fariborz Momenbeik,
Federica Carnamucio,
Nicola Micale
Affiliations
Zahra Kazemi
Department of Chemistry, University of Isfahan, Isfahan 81746-73441, Iran
Hadi Amiri Rudbari
Department of Chemistry, University of Isfahan, Isfahan 81746-73441, Iran
Nakisa Moini
Department of Chemistry, Faculty of Physics and Chemistry, Alzahra University, Vanak, Tehran 19938-91176, Iran
Fariborz Momenbeik
Department of Chemistry, University of Isfahan, Isfahan 81746-73441, Iran
Federica Carnamucio
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, Italy
Nicola Micale
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, Italy
Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal agents. This review covers some of the latest and most relevant achievements in the biological and pharmacological activity of important indole-containing metal complexes in the area of drug discovery.