ACS Omega (Oct 2018)
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
- Dilip K. Tosh,
- Antonella Ciancetta,
- Philip Mannes,
- Eugene Warnick,
- Aaron Janowsky,
- Amy J. Eshleman,
- Elizabeth Gizewski,
- Tarsis F. Brust,
- Laura M. Bohn,
- John A. Auchampach,
- Zhan-Guo Gao,
- Kenneth A. Jacobson
Affiliations
- Dilip K. Tosh
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- Antonella Ciancetta
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- Philip Mannes
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- Eugene Warnick
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- Aaron Janowsky
- VA Portland Health Care System, Research Service (R&D-22), and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, United States
- Amy J. Eshleman
- VA Portland Health Care System, Research Service (R&D-22), and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, United States
- Elizabeth Gizewski
- Department of Pharmacology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States
- Tarsis F. Brust
- Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida, United States
- Laura M. Bohn
- Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida, United States
- John A. Auchampach
- Department of Pharmacology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States
- Zhan-Guo Gao
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- Kenneth A. Jacobson
- Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States
- DOI
- https://doi.org/10.1021/acsomega.8b01237
- Journal volume & issue
-
Vol. 3,
no. 10
pp. 12658 – 12678
Abstract
No abstracts available.
