ARE THERE ANY VARIATION IN NEUTROPHIL LYMPHOCYTE RATIO, MEAN PLATELET VOLUME AND PLATELET COUNT BETWEEN PAPILLARY THYROID CANCER AND BENIGN NODULAR THYROID DISEASES

Abstract

Objective: Neutrophil lymphocyte ratio (N/L) and mean platelet (Plt) volume (MPV), the markers of systemic inflammatory response, has been investigated in many cancers, but data for head and neck cancers and thyroid carcinoma are limited. It had been purposed to study N/L, MPV, and Plt levels in papillary thyroid carcinoma (PTC) as a diagnostic marker. Material and Methods: A total of 104 patients, had undergone ultrasonography (US) guided fine needle aspiration (FNA) and thyroidectomy, for indicated cases, between April 2010 and August 2013, were enrolled in the study and the laboratory tests, regarding N/L, MPV, and Plt, of the cases had been collected retrospectively. Results: No any difference was stated between PTC and benign nodular thyroid diseases (BNTD) in terms of age, gender, size of the nodule, N/L, MPV, and Plt (p>0.05). Conclusion: The preoperative inflammatory hematological parameters, in terms of N/L, MPV, and Plt, may not be useful as a predictive diagnostic marker of the thyroid malignancy, PTC.

Keywords

• Thyroid neoplasms; Papillary thyroid cancer (PTC); Ultrasonography (US); Ultrasonography guided fine needle aspiration (US-g-FNA); Bethesda; Neutrophils; Lymphocytes; Neutrophil lymphocyte ratio; Mean platelet volume; Blood platelets
• Thyroid neoplasms
• Papillary thyroid cancer (PTC)
• Ultrasonography (US
• Ultrasonography guided fine needle aspiration (US-g-FNA
• Bethesda
• Neutrophils
• Lymphocytes
• Neutrophil lymphocyte ratio
• Mean platelet volume
• Blood platelets