South African Journal of Radiology (Jul 2024)

Multiple myeloma in a young female presenting as an aggressive skull-base tumour

  • Ursula Lesar,
  • Leon Janse van Rensburg,
  • Siobhan Oelofsen,
  • Kevin McCree,
  • Christelle Ackerman,
  • Razaan Davis

DOI
https://doi.org/10.4102/sajr.v28i1.2883
Journal volume & issue
Vol. 28, no. 1
pp. e1 – e5

Abstract

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Plasma cell neoplasia has a wide presentation of disease (localised or systemic) according to the International Myeloma Working Group. Radiological imaging identifies plasmacytomas as solitary lesions or part of multiple myeloma. We present a rare case of a 21-year-old female who presented with a skull-base tumour. Contribution: A head and neck plasmacytoma with further lytic bone lesions was confirmed on imaging. This article presents and discusses the clinical, CT, MRI, positron emission tomography (PET)-CT, histology and laboratory findings.

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