Image-based deep learning model to predict stoma-site incisional hernia in patients with temporary ileostomy: A retrospective study
Zhongyi Dong,
Jianhua Cai,
Haigang Geng,
Bo Ni,
Mengqing Yuan,
Yeqian Zhang,
Xiang Xia,
Haoyu Zhang,
Jie Zhang,
Chunchao Zhu,
Un Wai Choi,
Aksara Regmi,
Cheok I. Chan,
Cara Kou Yan,
Yan Gu,
Hui Cao,
Zizhen Zhang
Affiliations
Zhongyi Dong
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Jianhua Cai
Department of General Surgery, Fudan University Affiliated Huadong Hospital, Shanghai 200040, P.R. China
Haigang Geng
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Bo Ni
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Mengqing Yuan
School of Science, The Hongkong University of Science and Technology, Hongkong 999077, P.R. China
Yeqian Zhang
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Xiang Xia
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Haoyu Zhang
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Jie Zhang
Department of Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Chunchao Zhu
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China
Un Wai Choi
School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China
Aksara Regmi
School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China
Cheok I. Chan
School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China
Cara Kou Yan
School of Medicine, Shanghai Jiaotong University, Shanghai 200025, P.R. China
Yan Gu
Department of General Surgery, Fudan University Affiliated Huadong Hospital, Shanghai 200040, P.R. China; Corresponding author
Hui Cao
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China; Corresponding author
Zizhen Zhang
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R. China; Corresponding author
Summary: The prophylactic implantation of biological mesh can effectively prevent the occurrence of stoma-site incisional hernia (SSIH) in patients undergoing stoma retraction. Therefore, our study prospectively established and validated a mixed model, which combined radiomics, stepwise regression, and deep learning for the prediction of SSIH in patients with temporary ileostomy. The mixed model showed good discrimination of the SSIH patients on all cohorts, which outperformed deep learning, radiomics, and clinical models alone (overall area under the curve [AUC]: 0.947 in the primary cohort, 0.876 in the external validation cohort 1, and 0.776 in the external validation cohort 2). Moreover, the sensitivity, specificity, and precision for predicting SSIH were improved in the mixed model. Thus, the mixed model can provide more information for SSIH precaution and clinical decision-making.
