Acute and chronic inflammation alter immunometabolism in a cutaneous delayed-type hypersensitivity reaction (DTHR) mouse model

Laimdota Zizmare; Roman Mehling; Irene Gonzalez-Menendez; Caterina Lonati; Leticia Quintanilla-Martinez; Bernd J. Pichler; Manfred Kneilling; Christoph Trautwein

doi:10.1038/s42003-022-04179-x

Communications Biology (Nov 2022)

Acute and chronic inflammation alter immunometabolism in a cutaneous delayed-type hypersensitivity reaction (DTHR) mouse model

Laimdota Zizmare,
Roman Mehling,
Irene Gonzalez-Menendez,
Caterina Lonati,
Leticia Quintanilla-Martinez,
Bernd J. Pichler,
Manfred Kneilling,
Christoph Trautwein

Affiliations

Laimdota Zizmare: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tübingen
Roman Mehling: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tübingen
Irene Gonzalez-Menendez: Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University of Tübingen
Caterina Lonati: Center for Preclinical Research, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico
Leticia Quintanilla-Martinez: Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University of Tübingen
Bernd J. Pichler: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tübingen
Manfred Kneilling: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tübingen
Christoph Trautwein: Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tübingen

DOI: https://doi.org/10.1038/s42003-022-04179-x
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

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Nuclear magnetic resonance spectroscopy-based tissue metabolomics is used to define detailed temporal signatures of acute and chronic inflammation in cutaneous delayed-type hypersensitivity reaction.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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