Emerging Infectious Diseases (Jan 2023)

Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa

  • Yaovi M.G. Hounmanou,
  • Elisabeth Njamkepo,
  • Jean Rauzier,
  • Karin Gallandat,
  • Aurélie Jeandron,
  • Guyguy Kamwiziku,
  • Klaudia Porten,
  • Francisco Luquero,
  • Aaron Aruna Abedi,
  • Baron Bashige Rumedeka,
  • Berthe Miwanda,
  • Martin Michael,
  • Placide Welo Okitayemba,
  • Jaime Mufitini Saidi,
  • Renaud Piarroux,
  • François-Xavier Weill,
  • Anders Dalsgaard,
  • Marie-Laure Quilici

DOI
https://doi.org/10.3201/eid2901.220641
Journal volume & issue
Vol. 29, no. 1
pp. 149 – 153

Abstract

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Africa’s Lake Tanganyika basin is a cholera hotspot. During 2001–2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.

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