Pediatric Reports (May 2023)

Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México

  • Joel Barroso-Santos,
  • Angelina Ingrid Robledo-Martínez,
  • Sara Elva Espinosa-Padilla,
  • Rubén Genaro Hurtado del Ángel,
  • Felipe Arteaga-García,
  • Mónica Langarica-Bulos,
  • José Antonio Madrid-Gómez-Tagle,
  • Beatriz Adriana Sánchez-Reyes,
  • Sarai Eunice Hernández-Cadena,
  • Jorge Iván Suárez-Soto,
  • Carolina Delgado-Amézquita,
  • Brenda Godínez-Hernández,
  • Octavio Otamendi-Canales,
  • Angélica Saraí Jiménez-Osorio

DOI
https://doi.org/10.3390/pediatric15020030
Journal volume & issue
Vol. 15, no. 2
pp. 341 – 348

Abstract

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Multisystemic inflammatory syndrome (MIS-C) is an inflammatory condition temporally associated with COVID-19 in children; nevertheless, the clinical and immunologic spectrum of MIS-C is heterogeneous, and its long-term effects are unknown. During the period of August 2020 to December 2021, a total of 52 MIS-C cases were confirmed in pediatric patients from the Hospital del Niño DIF Hidalgo, diagnosed using criteria from the World Health Organization. All patients had serologic IgG confirmation of SARS-CoV2, the mean age of the patients was 7 years, and 94% of the patients did not have a previous underlying disease. In addition to the presentation of lymphopenia, neutropenia, and thrombocytopenia, elevations in D-dimer and ferritin levels were observed in all patients. There was clinical improvement with intravenous gamma globulin and corticosteroid treatment.

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