Romanian Neurosurgery (Mar 2024)
Cerebral hydatid cyst masquerading as multiple cystic metastases
Abstract
Hydatid disease is caused by encysted larvae of the dog tapeworm Echinococcus granulosus. Cerebral hydatidosis is a rare central nervous system larval infection affecting approximately 2–3% of patients. CT and MRI scans of the boy, described in our case, showed multiple cystic areas. Total surgical extirpation is the therapeutic approach, emphasizing the importance of early diagnosis for a favourable prognosis. Recurrence and unfavourable outcomes are commonly associated with incomplete excision and surgical rupture, necessitating careful removal to prevent anaphylaxis and widespread infection. Dowling's technique is the preferred surgical approach and postoperatively, patients are administered antiparasitic drugs such as Albendazole or Mebendazole for 6–12 months in most cases, with doses ranging from 10-15mg/kg in divided doses. The results of pharmacological treatment vary across series, with response rates ranging from 43.5 to 80%. Early diagnosis significantly contributes to a favourable prognosis by preventing neurological consequences.