Radioreparative Effect of Diode Laser on Leukopoiesis Recovery: A Pilot Study
Jaroslav Průcha,
Zuzana Šinkorová,
Anna Carrillo,
Tomáš Burda,
Julie Čuprová
Affiliations
Jaroslav Průcha
Department of Information and Communication Technologies in Medicine, Faculty of Biomedical Engineering, Czech Technical University in Prague, Sitna Sq. 3105, 272 01 Kladno, Czech Republic
Zuzana Šinkorová
Department of Radiobiology, Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 500 02 Hradec Králové, Czech Republic
Anna Carrillo
Department of Radiobiology, Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 500 02 Hradec Králové, Czech Republic
Tomáš Burda
Department of Information and Communication Technologies in Medicine, Faculty of Biomedical Engineering, Czech Technical University in Prague, Sitna Sq. 3105, 272 01 Kladno, Czech Republic
Julie Čuprová
Department of Healthcare and Population Protection, Faculty of Biomedical Engineering, Czech Technical University in Prague, Sitna Sq. 3105, 272 01 Kladno, Czech Republic
The aim of the present study was to investigate the effect of laser therapy on leukopoiesis recovery after irradiation with ionizing radiation. A dose of ionizing radiation was used that induced the hematological form of radiation sickness, reducing the number of blood cells. Subsequently, mice were treated with non-ionizing laser radiation. Based on the examination of the peripheral blood, the study found that laser therapy significantly impacted the number of eosinophils and basophils two weeks after irradiation. Laser therapy also led to the faster reparation of the lymphocyte lineage of white blood cells (WBCs). The research showed that the examined therapeutic laser had a long-term radioreparative effect on gamma-irradiated mice, improving the absolute counts of different lines of WBCs. The results of this study could have implications for the treatment of radiation sickness in humans.
