Recent advances in understanding urethral lichen sclerosus [version 1; referees: 3 approved]

Abstract

Lichen sclerosus affecting the male genitalia is a poorly understood but potentially devastating condition. The natural history of the condition is beginning to be understood better with longer follow-up of patients. Recent long-term data suggest that circumcision for lichen sclerosus limited to the prepuce may not be curative as was once thought. In addition, surgical treatments should be followed up for longer periods as recurrences may occur after urethroplasty and perineal urethrostomy.

Keywords

• Autoimmunity
• Benign Bladder & Urethral Disorders
• Cell Adhesion
• Cellular Death & Stress Responses
• Genito-Urinary & Reproductive Pharmacology
• Psoriasis & Other Inflammatory Diseases