Boron-mediated directed aromatic C–H hydroxylation

Jiahang Lv; Binlin Zhao; Yu Yuan; Ying Han; Zhuangzhi Shi

doi:10.1038/s41467-020-15207-x

Nature Communications (Mar 2020)

Boron-mediated directed aromatic C–H hydroxylation

Jiahang Lv,
Binlin Zhao,
Yu Yuan,
Ying Han,
Zhuangzhi Shi

Affiliations

Jiahang Lv: State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University
Binlin Zhao: State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University
Yu Yuan: College of Chemistry and Chemical Engineering, Yangzhou University
Ying Han: College of Chemistry and Chemical Engineering, Yangzhou University
Zhuangzhi Shi: State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University

DOI: https://doi.org/10.1038/s41467-020-15207-x
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 8

Abstract

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Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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