The acute and dermal toxicity of antiparasitic salt briquettes on laboratory animals

Abstract

The acute toxicity of salt briquettes with ivermectin is investigated. LD50 for white rats is 6400 mg/kg, white mice – 10300 mg/kg (8945÷10854). At drawing on the intact leather (skin) of rats LD50 makes more than 12500 mg/kg. The salt briquettes with ivermectin have no irritating action on rats at unitary drawing.

Keywords

• salt briquettes
• toxicity
• mice
• rats
• ld50
• irritating action