Direct-acting antiviral therapy may help restore HCV-induced impaired redox balance and liver fibrosis process

Bal Tayibe; Doğan Serdar; Özcan Oğuzhan; Çabalak Mehmet; Çirkin Berfin

doi:10.1515/tjb-2022-0081

Türk Biyokimya Dergisi (Nov 2022)

Direct-acting antiviral therapy may help restore HCV-induced impaired redox balance and liver fibrosis process

Bal Tayibe,
Doğan Serdar,
Özcan Oğuzhan,
Çabalak Mehmet,
Çirkin Berfin

Affiliations

Bal Tayibe: Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye
Doğan Serdar: Department of Biochemistry, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye
Özcan Oğuzhan: Department of Biochemistry, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye
Çabalak Mehmet: Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye
Çirkin Berfin: Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Mustafa Kemal University, Hatay, Türkiye

DOI: https://doi.org/10.1515/tjb-2022-0081
Journal volume & issue: Vol. 48, no. 1
pp. 44 – 50

Abstract

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The aim of this study was to investigate the changes in thiol/disulfide balance, pro-fibrotic mediators (transforming growth factor-beta [TGF-β] and periostin) and a potential biomarker for the prediction of HCV-induced HCC (3β-hydroxysterol Δ24-reductase [DHCR24]) during direct-acting antiviral (DAA) therapy in chronic hepatitis C (CHC) patients.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

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Abstract

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