What is new? An overview of the 2016 international publications on the efficacy and safety of nonsteroidal anti-inflammatory drugs

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of pathogenetic therapy for acute and chronic pain associated with rheumatic diseases. It would seem that NSAIDs are well studied: their pharmacological properties are known; the fields of their applications, the efficacy of the drugs in treating various diseases and pathological conditions, possible adverse reactions (ARs), and methods for their prevention have been identified. Nevertheless, this drug group has so far remained one of the most debated topics in the international medical literature. Debates continue about the therapeutic value of NSAIDs, the ratio of their therapeutic potential and the risk of complications, and the expediency of their long use in a number of nosological entities. There are constantly reports of new studies that modify the existing view on many aspects of using NSAIDs in real clinical practice. The paper gives a brief overview of some of the most interesting and significant works on NSAIDs, which appeared in the world medical press in the past 2016.

Keywords

• nonsteroidal anti-inflammatory drugs
• efficacy
• safety
• osteoarthritis
• cardiovascular complications
• nsaid enteropathy