Hepatitis Rebound after Infection with Yellow Fever Virus

Abstract

In 2018, yellow fever with hepatitis was diagnosed for 2 unvaccinated travelers returning to France from Brazil. Hepatitis persisted for >6 months; liver enzyme levels again increased 2 months after disease onset with no detection of yellow fever virus RNA or other pathogens. Persistent hepatitis with hepatic cytolysis rebound probably resulted from immune response.

Keywords

• Yellow fever
• persistent hepatitis
• Brazil
• viruses
• France
• hepatitis