Journal of Investigative Medicine High Impact Case Reports (Jun 2020)

–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage

  • Prateek S. Harne MD,
  • Samiran Mukherjee MD,
  • Ted Achufusi MD,
  • Dhruv Lowe MD,
  • Divey Manocha MD

DOI
https://doi.org/10.1177/2324709620937166
Journal volume & issue
Vol. 8

Abstract

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Primary gastric lymphoma is rare, representing 5% of all primary gastric neoplasms. The presenting complaints of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are usually nonspecific. However, life-threatening gastrointestinal bleeding from the stomach is unusual and sparsely reported. While studies reveal an indolent course, we present a case that presented with massive and recurrent hematemesis leading to hypovolemic shock secondary to endoscopically confirmed MALT lymphoma, which was treated with radiotherapy to achieve remission. She had no autoimmune diseases and tested negative for Helicobacter pylori . Our case emphasizes the importance of early diagnosis and timely intensive radiotherapy of a localized but aggressive gastric MALT lymphoma.