Hospital Pharmacology (Jan 2017)

Chromosomes aberations and enviromental factors

  • Marković Srđan Z.,
  • Nikolić Ljubinka I.,
  • Hamidović Jasmina Lj.,
  • Grubor Marija G.,
  • Grubor Milena M.,
  • Kastratović Dragana A.

DOI
https://doi.org/10.5937/hpimj1701486M
Journal volume & issue
Vol. 4, no. 1
pp. 486 – 490

Abstract

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Explanation the topic: Changes in genetic material can lead to aberrant cell in the direction of disorders of cellular regulation, malignant transformation, cell death, or if the adjustment was made at the level of the reproductive cells, to genetic changes in some of the consequent off spring. The topic position in scientific/professional public: Breaking of chromosomes can occur spontaneously or can be induced. Chromatid/chromosome breakings can be induced by different environmental factors: chemicals, biological clastogenic agents, accidentally or intentionally. Conclusions: The authors suggest: - making conditions for strong respect of environmental regulations; - to use higher plants for the early detection of environmental mutagens; - create and orderly update National radionuclide database.

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