CLINICAL, NEUROPHYSIOLOGICAL AND IMMUNOLOGICAL STUDIES OF CANCER PATIENTS WITH LESIONS OF THE PERIPHERAL NERVES

Abstract

Clinical electrophysiological and immunological studies of 88 cancer patients showed that in breast cancer and small lung cancer takes place symmetric, distal, sensory-motor, axonal-demyelinating polyneuropathy. Autoimmune nature of the disease confirmed onconeural antigens detected in the serum of more than half of the study participants.

Keywords

• рак молочной железы, мелкоклеточный рак легкого, паранеопластическая полиневропатия, аксонально-демиелинизирующий тип, онконевральные антигены, нейрональные антитела, химиотерапия, цитостатики, нейротоксичность