Healing of cutaneous wounds using GaAs laser in diabetic rat models

Abstract

Conventional treatment modalities usually fail to heal wounds in diabetic animals. Photomodulation of the wound bed using low-level laser has proved its efficacy in treating chronic wounds. Considering the fact that the majority of the diabetic wounds end up in amputation of affected part and reduce the quality of life of the patient, the present study was undertaken to find out the efficacy of gallium arsenide (GaAs) laser in the healing of full-thickness cutaneous wounds in type 2 diabetic rat models. The study was conducted in six adult male Wistar rats with an average body weight of 150 g in which hyperglycemia coexisting with hyperlipidemia was induced. Two wounds of 1 cm2 area were induced of which left side wounds served as the control and right side wounds were treated with GaAs laser at 4J/cm2 area for one minute continuously for four days.

Keywords

• type 2 diabetes
• streptozotocin
• gaas laser