Nature Communications (Feb 2023)

Molecular mechanisms of coronary artery disease risk at the PDGFD locus

  • Hyun-Jung Kim,
  • Paul Cheng,
  • Stanislao Travisano,
  • Chad Weldy,
  • João P. Monteiro,
  • Ramendra Kundu,
  • Trieu Nguyen,
  • Disha Sharma,
  • Huitong Shi,
  • Yi Lin,
  • Boxiang Liu,
  • Saptarsi Haldar,
  • Simon Jackson,
  • Thomas Quertermous

DOI
https://doi.org/10.1038/s41467-023-36518-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 17

Abstract

Read online

Genes encode risk for coronary disease, identifying how they function is critical to developing new therapies. In work reported the authors have identified one culprit gene, PDGFD, and studied how it functions to promote disease risk.